The vegetable capsule employs hpmc as its primary raw material, is higher in safety, does not include heat, has no heat-degradable animal gelatin protein, and does not contain any genetically modified raw materials.
A little water content. Normally 5% to 8%, which is ideal for pharmaceuticals or functional foods with high hygroscopicity and water sensitivity. A traditional Chinese medicine extract, for instance, typically has strong hygroscopicity and is easy to absorb water in gelatin capsules, leading to quality issues like caking of the capsule's contents, hardening of the shell, brittleness, disintegration time limit, or unqualified dissolution rate, etc. However, because hydroxypropyl methylcellulose is used as the capsule material, the water content in the capsule shell is lower than that of gelatin, the appearance and rate of dissolution are not sensitive to changes in the water content and environmental humidity in the capsule shell, and the product quality is simple to control.
Wide range of application The absence of interactions, great stability, and no risk of crosslinking reactions. Since hydroxypropyl methylcellulose is a derivative of cellulose, there is no risk of the amino acids in gelatin being cross-linked (after cross-linking, it is simple to cause disintegration or dissolution reduction), the drug release rate is comparatively stable, and individual differences are minimal.
Lax storage conditions restrictions. Low humidity (30%rh, brittle ratio = 2.1%), barely brittle; high temperature (80°C, capsule change 1.0%); good stability. Gelatin capsules have high requirements for storage environment temperature, humidity, and packaging materials because they are easily dehydrated and harden or brittle under high temperature and low humidity circumstances. Storage time also clearly affects the quality of gelatin capsules.
Excellent coating properties are present. For the creation of coated capsules with continuous and regulated releases, it is highly appropriate. Coating materials stick well and uniformly to plant capsules because hydroxypropyl methylcellulose has a good affinity for the majority of polymer compounds.
