1, Main components
Hydroxypropyl methylcellulose (HPMC):
Source: Plant based raw materials such as wood pulp, short cotton wool, etc.
Structure: A long-chain molecular structure composed of glucose units connected by β -1,4-glycosidic bonds. After etherification reaction, some hydroxyl groups are replaced by methoxy and hydroxypropyl groups.
Characteristics: It has good water solubility, film-forming ability, stability, and biocompatibility.
2, Auxiliary materials
When preparing HPMC capsules, in addition to the main component HPMC, some auxiliary materials may also be added to improve the performance of the capsules or meet specific application requirements.
These auxiliary materials may include:
Plasticizers: such as glycerol, sorbitol, etc., used to improve the flexibility and plasticity of capsule shells.
Lubricants, such as magnesium stearate, are used to improve the demolding performance of capsules in molds.
Antioxidants, such as vitamin E, are used to prevent capsules from oxidizing and deteriorating during storage.
Coloring agent: used to improve the appearance of capsules or meet specific labeling requirements.
3, Safety of ingredients
HPMC, as a semi synthetic cellulose ether, has undergone extensive safety evaluations.
It has good biocompatibility and low toxicity, and can be degraded into harmless substances in the human body.
The selection and use of excipients also need to comply with relevant safety standards and regulations to ensure the overall safety of the capsule.
