Do gelatine capsules clump together over time?

Oct 01, 2025

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Alex Zhang
Alex Zhang
As the Production Manager at Healsee Capsules, I oversee all manufacturing processes ensuring they meet GMP standards. Passionate about quality and innovation in capsule production.

Over the years, as a dedicated supplier of gelatine capsules, I've received numerous inquiries from clients regarding the long - term storage and quality of our products. One question that frequently pops up is: "Do gelatine capsules clump together over time?" In this blog, I'll draw on our in - depth knowledge and experience in the industry to provide a comprehensive answer to this question.

Understanding Gelatine Capsules

Before delving into the issue of clumping, it's essential to understand what gelatine capsules are. Gelatine is a protein obtained by partial hydrolysis of collagen, a fibrous protein found in the skin, bones, and connective tissues of animals. Our Hard Empty Gelatine Capsules are widely used in the pharmaceutical, nutraceutical, and food industries due to their excellent biocompatibility, easy - to - swallow nature, and ability to protect the enclosed substances from environmental factors.

Factors Affecting Clumping

Moisture

Moisture is one of the primary culprits behind the clumping of gelatine capsules. Gelatine is a hygroscopic material, which means it has a strong affinity for water. When gelatine capsules are exposed to a high - humidity environment, they absorb moisture from the air. This absorbed moisture can cause the gelatine to soften and become sticky. As a result, the capsules may adhere to each other, forming clumps.

For example, if you store gelatine capsules in a bathroom cabinet where the humidity is often high due to showers, you're more likely to notice clumping. On the other hand, if the storage environment is too dry, the gelatine can lose its natural moisture content, become brittle, and may also develop issues such as cracking, which can indirectly lead to problems during handling and use.

Temperature

Temperature also plays a significant role in the stability of gelatine capsules. High temperatures can accelerate the physical and chemical changes in gelatine. When gelatine capsules are exposed to elevated temperatures, the protein structure of the gelatine can start to break down. This breakdown can lead to changes in the mechanical properties of the capsules, making them more likely to stick together.

In addition, temperature fluctuations can cause condensation inside the storage containers. If the temperature drops suddenly, the moisture in the air inside the container can condense on the surface of the capsules. This moisture can then trigger the clumping process. For instance, if you store gelatine capsules in a place where there are significant temperature differences between day and night, such as an uninsulated shed, the capsules are at a higher risk of clumping.

Storage Conditions

The way gelatine capsules are stored can have a profound impact on their long - term quality. Improper storage, such as overcrowding the capsules in a container, can increase the likelihood of clumping. When capsules are packed too tightly, there is less air circulation around them. This lack of air circulation can trap moisture and heat, creating a micro - environment that is conducive to clumping.

Moreover, the type of storage container matters. If the container is not airtight, it allows moisture and air to enter, increasing the risk of clumping. A good storage container should be made of a material that is resistant to moisture and should have a tight - fitting lid to prevent the entry of external humidity.

Preventive Measures

Optimal Storage Conditions

To prevent gelatine capsules from clumping, it's crucial to store them under optimal conditions. The ideal storage temperature for gelatine capsules is between 15°C and 25°C (59°F and 77°F), and the relative humidity should be maintained between 35% and 60%. A cool, dry place away from direct sunlight is the best choice. For example, a pantry or a dedicated storage room with climate control can be suitable locations.

Use of Desiccants

Desiccants are substances that can absorb moisture from the surrounding environment. Placing desiccants such as silica gel packets inside the storage container can help keep the humidity levels low. Silica gel is a common desiccant used in the packaging industry because it is non - toxic, odorless, and can effectively absorb moisture. Just make sure to replace the desiccants regularly to maintain their effectiveness.

Proper Packaging

At our company, we pay great attention to the packaging of our gelatine capsules. We use high - quality, airtight packaging materials to protect the capsules from external moisture and air. Our packaging is designed to provide a barrier against environmental factors, ensuring that the capsules remain in good condition during transportation and storage.

Quality Control in Production

As a gelatine capsule supplier, we have a strict quality control system in place to ensure the long - term stability of our products. During the production process, we carefully monitor the moisture content of the gelatine. We use advanced technology to control the drying process, ensuring that the capsules have the appropriate moisture level to maintain their integrity.

We also conduct regular quality tests on our products. These tests include checking the mechanical properties of the capsules, such as their hardness and brittleness, as well as their resistance to environmental factors. By doing so, we can identify any potential issues early and take corrective measures to ensure that our customers receive high - quality gelatine capsules.

Our Commitment to Customers

We understand that the quality of our gelatine capsules is of utmost importance to our customers. That's why we are committed to providing not only high - quality products but also excellent customer service. If you have any questions or concerns about the storage or use of our gelatine capsules, our team of experts is always ready to assist you.

We also offer customized solutions to meet the specific needs of our customers. Whether you need a particular size, shape, or color of gelatine capsules, we can work with you to develop the perfect product for your application.

Hard Empty Gelatine Capsulescolored vegetable capsules

Contact Us for Procurement

If you're interested in purchasing our Hard Empty Gelatine Capsules, we encourage you to get in touch with us. We believe that our products can meet your requirements in terms of quality, performance, and price. Whether you're a small - scale pharmaceutical company or a large - scale nutraceutical manufacturer, we have the capacity to supply you with the right quantity of gelatine capsules.

Contact us today to start a procurement discussion. Our sales team will be happy to provide you with detailed product information, pricing, and delivery options. We look forward to establishing a long - term business relationship with you.

References

  • "Handbook of Pharmaceutical Excipients" - A comprehensive reference book that provides detailed information on the properties and applications of various pharmaceutical excipients, including gelatine.
  • Industry research reports on the gelatine capsule market, which often contain data on product quality and stability.
  • Internal research and development reports from our company, which document our findings on the factors affecting the quality of gelatine capsules and our strategies for quality control.
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